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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCYT1A
All Species:
22.12
Human Site:
S56
Identified Species:
34.76
UniProt:
P49585
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49585
NP_005008.2
367
41731
S56
D
E
I
E
V
D
F
S
K
P
Y
V
R
V
T
Chimpanzee
Pan troglodytes
XP_001143741
320
37092
E32
A
P
A
P
F
A
D
E
T
N
C
Q
C
Q
A
Rhesus Macaque
Macaca mulatta
XP_001090055
338
38695
E50
A
P
A
P
F
A
D
E
T
N
C
Q
C
R
A
Dog
Lupus familis
XP_535776
367
41764
S56
D
E
I
E
V
D
F
S
K
P
Y
V
R
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P49586
367
41648
S56
D
E
I
E
V
D
F
S
K
P
Y
V
R
V
T
Rat
Rattus norvegicus
P19836
367
41662
S56
D
E
I
E
V
D
F
S
K
P
Y
V
R
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517894
294
33692
Chicken
Gallus gallus
XP_422725
367
42078
S56
D
E
V
E
I
D
Y
S
K
P
Y
I
R
V
T
Frog
Xenopus laevis
NP_001089299
367
41920
S56
D
E
L
K
V
D
R
S
K
P
Y
R
R
V
S
Zebra Danio
Brachydanio rerio
NP_001018571
359
41135
E53
A
D
E
L
V
T
P
E
S
A
Y
A
R
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647621
526
58183
R185
E
A
M
L
E
R
D
R
C
D
Y
T
Q
R
I
Honey Bee
Apis mellifera
XP_395764
403
46370
A93
E
A
L
A
E
R
N
A
C
D
Y
N
I
R
I
Nematode Worm
Caenorhab. elegans
P49583
362
41751
A60
L
A
I
T
T
R
E
A
V
D
Y
S
K
K
I
Sea Urchin
Strong. purpuratus
XP_001180754
425
48260
Q72
F
G
S
E
Q
E
K
Q
R
W
D
F
T
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13259
424
49388
K83
R
Y
T
N
E
L
P
K
E
L
R
K
Y
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.5
60.7
96.4
N.A.
96.1
96.4
N.A.
77.3
89
86.3
76.2
N.A.
36.1
46.4
37.8
45.4
Protein Similarity:
100
69.2
71.6
98
N.A.
97.5
97.2
N.A.
78.1
95
91.2
84.1
N.A.
46
62
52.3
60
P-Site Identity:
100
0
0
100
N.A.
100
100
N.A.
0
73.3
66.6
26.6
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
0
0
100
N.A.
100
100
N.A.
0
100
86.6
40
N.A.
26.6
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
14
7
0
14
0
14
0
7
0
7
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
14
0
14
0
14
0
0
% C
% Asp:
40
7
0
0
0
40
20
0
0
20
7
0
0
0
0
% D
% Glu:
14
40
7
40
20
7
7
20
7
0
0
0
0
0
0
% E
% Phe:
7
0
0
0
14
0
27
0
0
0
0
7
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
34
0
7
0
0
0
0
0
0
7
7
0
20
% I
% Lys:
0
0
0
7
0
0
7
7
40
0
0
7
7
7
0
% K
% Leu:
7
0
14
14
0
7
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
0
0
14
0
7
0
0
0
% N
% Pro:
0
14
0
14
0
0
14
0
0
40
0
0
0
7
7
% P
% Gln:
0
0
0
0
7
0
0
7
0
0
0
14
7
7
0
% Q
% Arg:
7
0
0
0
0
20
7
7
7
0
7
7
47
27
0
% R
% Ser:
0
0
7
0
0
0
0
40
7
0
0
7
0
0
14
% S
% Thr:
0
0
7
7
7
7
0
0
14
0
0
7
7
0
34
% T
% Val:
0
0
7
0
40
0
0
0
7
0
0
27
0
47
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
7
0
0
0
0
7
0
0
0
67
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _